New research exposes hidden vulnerability in novel Coronavirus

By Nikita Chaurasia  | Date: 2020-08-12

New research exposes hidden vulnerability in novel Coronavirus

The research led by Monica Olvera de la Cruz, Lawyer Taylor Professor of Materials Science and Engineering, and Baofu Qiao, a research assistant professor at the Northwestern University, have reportedly discovered a new vulnerability in the SARS-CoV-2 spike protein, indicating a relatively simple treatment route.

For those unfamiliar, the binding site present in the spike protein on attaching to host cells allows the virus to enter and multiply inside the body. Researchers were able to discover polybasic cleavage site, a positively charged site situated 10 nanometers from the actual binding site.

This positively charged site reportedly enables a strong bond between the spike protein and negatively charged human-cell receptors. Upon this discovery, the researchers devised a way to prevent the virus from bonding to the host cell by designing a negatively charged molecule that could bind with the positively charged cleavage site, cite credible sources.

Olvera de la Cruz claimed that the blocking the cleavage site could be a preventive treatment to reduce the virus’ capability of infecting human cells. The research shows that mutations of the SARS-CoV-2 spike protein impacted the transmission of the virus, she emphasized.  

The research was backed by the U.S. Department of Energy, Northwestern University’s Center for Computation and Theory of Soft Materials, and the Sherman Fairchild Foundation, claim sources.

With this new-found data, the researchers are eyeing to collaborate with Northwestern pharmacologists and chemists to develop a drug that could bind to the spike protein.

In another major development, Russain Microbiology Research Center Gamaleya have already announced the world’s first coronavirus vaccine.

The quest for finding a vaccine to combat the novel coronavirus, which was declared a pandemic on March 11 by the WHO, may finally reach a conclusion with many possible cures emerging into the scene.  

Sources:

https://news.northwestern.edu/stories/2020/08/research-exposes-new-vulnerability-in-sars-cov-2/

https://www.dnaindia.com/world/report-russia-registers-world-s-first-coronavirus-vaccine-president-putin-s-daughter-vaccinated-2837128/amp

About Author

Nikita Chaurasia     aeresearch.net

Nikita Chaurasia

An accomplished professional in the field of content development, playing with words comes naturally to Nikita Chaurasia. After completing her post-graduate MBA degree in Advertising and PR, Nikita worked across numerous content-driven verticals, undertaking diverse r...

Read More >>

More News By Nikita Chaurasia

L&T Technology Services partners with Qualcomm to amplify 5G adoption

L&T Technology Services partners with Qualcomm to amplify 5G adoption

By Nikita Chaurasia

L&T Technology Services Limited has recently announced that it is teaming up with Qualcomm Technologies, Inc., the world’s leading wireless technology innovator. With the latest collaboration, the firm plans to offer end-to-end solutions...

PNAS, Straive partner to deliver end-to-end content production services

PNAS, Straive partner to deliver end-to-end content production services

By Nikita Chaurasia

Renowned U.S.-based nonprofit and non-governmental organization, NAS (National Academy of Sciences), has reportedly collaborated with Straive, one of the leading technology-driven solutions providers for Content, EdTech, and Data. With this acquis...

Japan pushes innovations in 'deep tech' sector with solar cell technology

Japan pushes innovations in 'deep tech' sector with solar cell technology

By Nikita Chaurasia

Amid the most promising next-generation solar cell technology innovations, Enecoat Technologies, a provider of materials development services in Japan, is reportedly developing perovskite. Following its completion, the Kyoto-located start-up expec...

GIC to acquire majority shares in opulent Sani/Ikos properties

GIC to acquire majority shares in opulent Sani/Ikos properties

By Nikita Chaurasia

Singapore's sovereign wealth fund, GIC has agreed to pay around $2.2 billion to buy a majority stake in Sani/Ikos Group, a Mediterranean luxury resort operator, marking the largest transaction in the European resort market since the Covid-19 pand...

Excelra, Patcore partner to offer enhanced digital insights to customers

Excelra, Patcore partner to offer enhanced digital insights to customers

By Nikita Chaurasia

Excelra, a data and analytics solutions provider, has recently announced its partnership with Patcore, Inc., to provide better access to its analytics products and scientific data for customers in Japan. For the unversed, Excelra is one of the top...